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Stimulation of hydroxylation and protein binding of the carcinogen 2-acetylaminofluorene in rat liver homogenates

โœ Scribed by J.H. Peters; H.R. Gutmann

Book ID
118841031
Publisher
Elsevier Science
Year
1956
Tongue
English
Weight
180 KB
Volume
62
Category
Article
ISSN
0003-9861

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The carcinogen 2-acetylaminofluorene inh
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โœ Birgitte Lindeman; Ellen Skarpen; Morten P. Oksvold; Henrik S. Huitfeldt ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 275 KB

Growth arrest in G 1 is a common cellular response to DNA damage. In the present study, liver regeneration was combined with continuous exposure for 2-acetylaminofluorene (AAF) to study mechanisms of carcinogen-induced growth arrest in vivo. Growth arrest of uninitiated hepatocytes is central for AA