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Stimulation of hamster sperm capacitation and acrosome reaction in vitro by glucose and lactate and inhibition by the glycolytic inhibitor ?-chlorohydrin

✍ Scribed by Dravland, Eric ;Meizel, Stanley

Book ID
111662829
Publisher
Wiley (John Wiley & Sons)
Year
1981
Weight
599 KB
Volume
4
Category
Article
ISSN
0148-7280

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Inhibition of the hamster sperm acrosome
Inhibition of the hamster sperm acrosome reaction by transmethylation inhibitors
✍ Meizel, Stanley πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 331 KB

## Abstract Two inhibitors of somatic cell transmethylation, homocysteine thiolactone (Hcy) and 3–deazadenosine (3–DZA), inhibited the acrosome reactions of hamster sperm in vitro. Hcy (250 ΞΌM) or 3–DZA (200 ΞΌM) inhibited acrosome reactions by approximately 30% after 4 hours of incubation with wash