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Stimulation of cGMP-dependent protein kinase (G-kinase) by peptide-546

✍ Scribed by J.P. Huggins; A.J. Ganzhorn; V. Saudek; J.T. Pelton; R.A. Atkinson


Book ID
113237383
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
131 KB
Volume
26
Category
Article
ISSN
0143-4179

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The second messenger cGMP is a major intracellular mediator of the vaso-active agents nitric oxide and natriuretic peptides. The principal targets of cGMP are (i) phosphodiesterases, resulting in interference with the cAMP-signalling pathway, (ii) cGMP-gated cation channels, and (iii) cGMP-dependent