## Abstract The effect on intraosseous bone formation of a single local injection of recombinant human basic fibroblast growth factor into the distal femur was examined in normal and ovariectomized rabbits. In normal rabbits, basic fibroblast growth factor increased bone mineral density around the
Stimulation of Bone Formation by Recombinant Fibroblast Growth Factor-2 in Callotasis Bone Lengthening of Rabbits
β Scribed by H. Okazaki; T. Kurokawa; K. Nakamura; T. Matsushita; K. Mamada; H. Kawaguchi
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 884 KB
- Volume
- 64
- Category
- Article
- ISSN
- 1432-0827
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## Abstract The effects of a single local injection of recombinant human fibroblast growth factorβ2 on the healing of segmental bone defects were evaluated in rabbits. One month after the external fixator originally designed for this experiment was installed in the tibia of the rabbit, a 3βmm bone
The effect of basic fibroblast growth factor (bFGF) applied locally into the bone under physiological conditions was investigated. An aqueous solution containing Ogg (vehicle), 100 gg or 400 gg recombinant human bFGF was percutaneously applied through a needle into the right ilium in rabbit, and the