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Stimulating effects of fibroblast growth factors on hepatic function of fetal liver cells synergistically with oncostatin M in three-dimensional culture

โœ Scribed by Kazunori Minagawa; Toshie Koyama; Hirotoshi Miyoshi


Book ID
113682550
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
665 KB
Volume
107
Category
Article
ISSN
1389-1723

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Oncostatin M stimulates proliferation an
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## Abstract In order to develop a tissue engineered bioartificial liver (BAL), longโ€term threeโ€dimensional (3โ€D) culture of fetal liver cells (FLCs) utilizing porous polymer as a scaffold was performed for up to 1 month. The effects of the basal medium and supplementation with oncostatin M (OSM) on

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## Abstract Vascular endothelial growth factor (VEGF) is crucial for the development and regeneration of the liver. However, there have been no reports about VEGF secretion by cultured fetal liver cells (FLCs). In the present study, the effects of oncostatin M (OSM), which strongly stimulates the g