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Sterol pathway in yeast. Identification and properties of mutant strains defective in mevalonate diphosphate decarboxylase and farnesyl diphosphate synthetase

✍ Scribed by Christophe Chambon; Veronique Ladeveze; Madeleine Servouse; Laurence Blanchard; Catherine Javelof; Barbu Vladescu; Francis Karst


Book ID
112774334
Publisher
Springer-Verlag
Year
1991
Tongue
English
Weight
466 KB
Volume
26
Category
Article
ISSN
0024-4201

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Isolation and properties of yeast mutant
✍ C. Chambon; V. Ladeveze; A. Oulmouden; M. Servouse; F. Karst 📂 Article 📅 1990 🏛 Springer-Verlag 🌐 English ⚖ 631 KB

Two yeast mutant strains auxotrophic for ergosterol and blocked in farnesyl diphosphate synthetase (EC 2.5.1.1) were isolated. Genetic analysis has shown that these mutant strains carry additional mutations in the ergosterol pathway besides erg20-1 and erg20-2 which affect FPP synthetase. The novel