von Hand eingestellt werden. Die gleiche Teniperaturprogrammiereinheit steht hiebei im Temperaturintervall von 25 bis 60" in Stufen von 1" Abstand zur Verfiigung. Ein sclbstcntwickelter Tcmperaturregler mit Differentialeingang sorgt dafiir, dass die Temperaturiiberhohung des Luftthermostaten gegenii
Steroid total synthesis. 11. (+)-Estr-4-ene-3,17-dione from a chiral lactone
✍ Scribed by Rosenberger, Michael; Borer, Rene; Saucy, Gabriel
- Book ID
- 120408292
- Publisher
- American Chemical Society
- Year
- 1978
- Tongue
- English
- Weight
- 850 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
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## Abstract An efficient and practical synthesis of the title compounds is described. The novel route is based on earlier results and uses (±)‐5‐hydroxy‐9,9‐__o__‐phenylenedioxy‐decanoic acid lactone as the starting material. The results demonstrate the usefulness of pyrocatechol for the protection
AbstractÐAn ef®cient synthesis has been developed affording 11b-(4-aminophenyl)spiro[estr-4-ene-17b,2 H (5 H H)-furan]-3,5 H -dione (2), main metabolite of antiprogestin (Z)-11b-[4-(dimethylamino)phenyl]-17b-hydroxy-17a-(3-hydroxyprop-1-enyl)estr-4-en-3-one (1), in an overall yield of 21%.