𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Steroid hormone alteration of herpes simplex virus type 1 replication

✍ Scribed by Mary F. D. Notter; John J. Docherty

Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
368 KB
Volume
2
Category
Article
ISSN
0146-6615

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The effect of steroid hormones on herpes simplex virus type 1 replication was examined. Virus replication studies revealed that various concentrations of prednisolone, hydrocortisone, dexamethasone, or progesterone could decrease virus yields up to a maximum of 99%. Using isopycnic centrifugation in CsCl to separate viral from cell DNA, it was found that virus‐specific DNA synthesis was decreased by 30 to 100% depending on the hormone and concentration used. Cell‐specific DNA synthesis was also adversely affected, but this did not alter cell viability or plating efficiency.

πŸ“œ SIMILAR VOLUMES

Hormonal modulation of herpes simplex vi
Hormonal modulation of herpes simplex virus replication in a mouse neuroblastoma cell line
✍ Gamil P. Sawiris; Dr. Robert J. Sydiskis; Nasir Bashirelahi πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 497 KB

In this study, the effect of the synthetic glucocorticoid hormone dexamethasone (DXM) on HSV replication was studied in a DXM receptor-positive mouse neuroblastoma (NB) cell line. In cells treated with 10-7M DXM and then infected with HSV, there was a statistically significant 9-1 8-fold increase in

Herpes simplex virus type 1 can either s
Herpes simplex virus type 1 can either suppress or enhance human immunodeficiency virus type 1 replication in CD4-positive T lymphocytes
✍ Arianna Calistri; Cristina Parolin; Giorgio PalΓΉ πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 191 KB

It was proposed recently that CEM CD4-positive T cells infected chronically by herpes simplex virus type 1 (HSV-1) and human immunodeficiency virus type 1 (HIV-1) (CEM(HSV/HIV)) may be used as a model for studying HIV/HSV interactions. To ascertain whether HSV-HIV coinfection of T lymphocytes has a