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Steric parameters in structure-activity correlations: cholinesterase inhibitors

โœ Scribed by Hansch, Corwin.


Book ID
126879547
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
267 KB
Volume
35
Category
Article
ISSN
0022-3263

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Structure-activity correlation study of
โœ Supa Hannongbua; Luckhana Lawtrakul; Jumras Limtrakul ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer Netherlands ๐ŸŒ English โš– 566 KB

Quantitative structure-activity relationships (QSARs) for 40 HIV-1 inhibitors, 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine and its derivatives, were studied. Fully optimized geometries, based on the semiempirical AM1 method, were used to calculate electronic and molecular properties of all com