The use of cholinesterase (CHE) inhibitors provided valuable information about the mechanism(s) of neuromuscular transmission, but questions on side effects at the level of ACh-activated channels were raised. Patch-clamp recording was used to study the effects of prostigmine (PST) and methanesulfony
Structure-activity relationship of reversible cholinesterase inhibitors including paraquat
✍ Scribed by Yasuo Seto; Toshiaki Shinohara
- Book ID
- 104719623
- Publisher
- Springer-Verlag
- Year
- 1988
- Tongue
- English
- Weight
- 384 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0340-5761
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Structure‐based quantitative structure‐activity relationship (QSAR) studies on a series of checkpoint kinase 1 (Chk1) inhibitors were performed to find the key structural features responsible for their inhibitory activity. Molecular docking was employed to explore the binding mode of al
## Abstract Aiming at new drugs to efficiently treat diseases, in which either increased or decreased levels of active vitamin D are desirable, we have designed some 400 structurally different azole‐type inhibitors and examined their capacity to selectively block vitamin D metabolism by CYP24 or sy