Steric Hindrance in Ketone—Phenol Condensations. The Condensation of Guaiacol with Cyclic Ketones
✍ Scribed by Niederl, Joseph B.; Niederl, Victor; Grumer, Joseph
- Book ID
- 127394583
- Publisher
- American Chemical Society
- Year
- 1940
- Tongue
- English
- Weight
- 316 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0002-7863
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📜 SIMILAR VOLUMES
Electrophilic condensation of pyrimidines with cyclic ketones was investigated. As nucleophiles,the degreeof ionizationof pyrimidinesin acidicmedia and the electrondensityon the C-5 determinedthe reactivity.An electron-richnitrogenat the 4-positionof cyclic ketonesfacilitatedthe reaction.This methcd
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