We describe here a synthesis of the morphine partial structures **28** and **36**, and of their enantiomers, which uses 7‐methoxy‐benzofurancarboxylic acid as starting material. A key intermediate in this scheme is compound **15**, which is converted, __via__ 1,2‐ketone shift, into **22**. This latt
Stereospezifische Synthese einer neuen Morphin-Teilstruktur
✍ Scribed by Walter Haefliger; Edgar Klöppner
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- German
- Weight
- 1019 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract **Synthesis of New Morphine Partial Structure 15,16‐Secomorphinan** The synthesis of a new morphine partial structure, 15,16‐secomorphinan, is described. One of the series, (±)‐15, 16‐secocyclorphan **(5)**, has the analgesic potency of morphine and exhibits good binding to the opiate
Charge-Transfer(CT)-Marker wie 5-(Dimethylamino)naphthalin-1-sulfonyl(Dansyl)-chlorid wurden in groûem Ausmaû beim Nachweis sowie bei der Charakterisierung und Lokalisierung von Kohlenhydraten, Phospolipiden, Proteinen, Oligonucleotiden sowie zahlreichen anderen synthetischen und natürlich vorkommen
**Contributions for a new synthesis of Cephem compounds.** Compounds **10** and **12** of type **2** were synthesized by pyrolysis of phenoxy‐urethanes **9** and **11**. The unsaturated side chain was synthesized by __Michael__‐addition of **7** to propiolic acid. Intramolecular [2 + 2]‐Cycloadditi