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Stereospecificity of the allosteric NADH dehydrogenase from Mycobacterium tuberculosis

โœ Scribed by A. Worcel; Dexter S. Goldman


Book ID
118845693
Publisher
Elsevier Science
Year
1967
Tongue
English
Weight
332 KB
Volume
118
Category
Article
ISSN
0003-9861

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The preferred antitubercular drug isoniazid specifically targets a long-chain enoyl-acyl carrier protein reductase (InhA), an enzyme essential for mycolic acid biosynthesis in__Mycobacterium tuberculosis__. Despite the widespread use of this drug for more than 40 years, its precise mode of action ha