Modification of the NADH of the Isoniazi
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Rozwarski, D. A.
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Article
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1998
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American Association for the Advancement of Scienc
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English
β 382 KB
The preferred antitubercular drug isoniazid specifically targets a long-chain enoyl-acyl carrier protein reductase (InhA), an enzyme essential for mycolic acid biosynthesis in__Mycobacterium tuberculosis__. Despite the widespread use of this drug for more than 40 years, its precise mode of action ha