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Stereospecific total synthesis and absolute configuration of a macrocyclic lactone antibiotic, A26771B

✍ Scribed by Kuniaki Tatsuta; Akira Nakagawa; Shunji Maniwa; Mitsuhiro Kinoshita


Publisher
Elsevier Science
Year
1980
Tongue
French
Weight
268 KB
Volume
21
Category
Article
ISSN
0040-4039

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✦ Synopsis


The total synthesis of a sixteen-membered macrocyclic lactone antibiotic, A26771B

and its absolute configuration are described by using D-glucose as a chiral source.

A 16-membered macrocyclic lactone antibiotic A26771B (&), p reduced by PeraiciZZium turbatwn,


📜 SIMILAR VOLUMES


Total Synthesis and Absolute Configurati
✍ K. C. Nicolaou; Yee Hwee Lim; Jochen Becker 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 449 KB

## Abstract **Einladung zum T**: Erstmals wurde der T‐förmige Bisanthrachinon‐Naturstoff BE‐43472B durch Totalsynthese hergestellt und seine Absolutkonfiguration aufgeklärt. Wesentliche Schritte der zentralen Kaskadensequenz sind eine Diels‐Alder‐Reaktion, die Bildung eines Halbketals und eine nucl

Total Synthesis and Absolute Configurati
✍ K. C. Nicolaou; Yee Hwee Lim; Jochen Becker 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 449 KB

## Abstract **An‐T‐biotic**: The first total synthesis of the T‐shaped bisanthraquinone natural product BE‐43472B was accomplished and its absolute configuration assigned. Key transformations in the pivotal cascade sequence include a Diels–Alder reaction, a hemiketal formation, and a nucleophilic a