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Stereospecific synthesis of racemic (cis-6-methyltetrahydropyran-2-yl)acetic acid, a constituent of the glandular secretion from the civet cat

✍ Scribed by Kim, Youseung; Mundy, Bradford P.


Book ID
127016904
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
285 KB
Volume
47
Category
Article
ISSN
0022-3263

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✍ Cornelius Nussbaumer; Georg FrΓ‘ter πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 German βš– 386 KB

Similar cyclizations to tetrahydropyrans are known [lo] to occur when 4-methyl-4-pentcn-2-01 Is condensed with aldehydes under acidic conditions (Kriewitz-Prim reaction [l I]). A /I-alkenyloxyacrylate cyclization has already found use in a stereoselective synthesis of (i)-cis-a-irone [ 161.