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Stereospecific synthesis of a (1→5)-α-L-arabinan

✍ Scribed by Leon V. Backinowsky; Sergei A. Nepogod'ev; Nikolay K. Kochetkov


Book ID
102641403
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
167 KB
Volume
137
Category
Article
ISSN
0008-6215

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A convenient route to make a-hydrazino esters from their corresponding a-amino esters is reported. A key step is selective nitrosamine reduction using activated Zn, conc. HCl, and methanol at low temperatures giving nearly quantitative yields of the pure a-hydrazino esters