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Stereospecific microbial reduction of 4,5-dihydro-4-(4-methoxyphenyl)-6-(trifluoromethyl-1H-1)-benzazepin-2-one

✍ Scribed by Ramesh N. Patel; Robert S. Robison; Laszo J. Szarka; John Kloss; John K. Thottathil; Richard H. Mueller


Book ID
103521835
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
635 KB
Volume
13
Category
Article
ISSN
0141-0229

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## Abstract 1,1,1‐Trifluoroalkane‐2,3‐dione 3‐oximes 1 easily obtainable from aldehyde dimethylhydrazones were reacted with several aldehydes and ketones in the presence of acetic acid to afford 4‐trifluoromethyl‐4__H__‐[1,5,2]dioxadines 3 in satisfactory yields. When the reaction was carried out i