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Stereoselective α-Amidoalkylation Reactions of Phenylglycinol-Derived Bicyclic Lactams.

✍ Scribed by Mercedes Amat; Carmen Escolano; Nuria Llor; Marta Huguet; Maria Perez; Joan Bosch

Publisher
John Wiley and Sons
Year
2003
Weight
134 KB
Volume
34
Category
Article
ISSN
0931-7597

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📜 SIMILAR VOLUMES

Stereoselective α-Amidoalkylation of Phe
Stereoselective α-Amidoalkylation of Phenylglycinol-Derived Lactams. Synthesis of Enantiopure 5,6-Disubstituted 2-Piperidones.
✍ Mercedes Amat; Carmen Escolano; Arantxa Gomez-Esque; Oscar Lozano; Nuria Llor; R 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 27 KB

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A Simple Stereoselective Synthesis of En
A Simple Stereoselective Synthesis of Enantiopure 2-Substituted Pyrrolidines and Piperidines from Chiral (R)-Phenylglycinol-Derived Bicyclic 1,3-Oxazolidines
✍ José M. Andrés; Ignacio Herráiz-Sierra; Rafael Pedrosa; Alfonso Pérez-Encabo 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 319 KB 👁 2 views

Chiral, nonracemic 2-substituted pyrrolidines and piperidines were prepared in high ee and moderate to good chemical yields in three steps from (R)-phenylglycinol and γ-or δchloroketones. The key step of the synthesis was the stereo-