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Stereoselective Total Synthesis of Natural (+)-Streptazolin via a Palladium-Catalyzed Enyne Bicyclization Approach

โœ Scribed by Yamada, Hironari; Aoyagi, Sakae; Kibayashi, Chihiro


Book ID
126254865
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
245 KB
Volume
118
Category
Article
ISSN
0002-7863

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Abstmct: Bifurcation of the synthetic pathway affording total syntheses of picrotoxinin, picrotin and corianin from a common synthetic intermediate daived via the palladium catalyzed enyne cycloisomerization leads to the total synthesis of the picrotoxane sesquiterpene methyl picrotoxate.