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Stereoselective total synthesis of (.+-.)-atisine via intramolecular double Michael reaction

✍ Scribed by Ihara, Masataka.; Suzuki, Makoto.; Fukumoto, Keiichiro.; Kametani, Tetsuji.; Kabuto, Chizuko.


Book ID
120980830
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
260 KB
Volume
110
Category
Article
ISSN
0002-7863

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An enantioselective synthesis of a 6oxygenated atisine derivative 20 is described. The atisine skeleton 18 was stereoselectively constructed by the intramolecular double Michael reaction of the enone ester 16. derived. through the al&hy& 3, from the symmetrical ketone 4. The diterpenoid alkaloids ha