Enantioselective synthesis of 6-oxygenat
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Masataka Ihara; Akihito Hirabayashi; Nobuaki Taniguchi; Keiichiro Fukumoto
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Article
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1992
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Elsevier Science
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French
β 730 KB
An enantioselective synthesis of a 6oxygenated atisine derivative 20 is described. The atisine skeleton 18 was stereoselectively constructed by the intramolecular double Michael reaction of the enone ester 16. derived. through the al&hy& 3, from the symmetrical ketone 4. The diterpenoid alkaloids ha