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Stereoselective total synthesis of (±)-antheridic acid

✍ Scribed by Masanao Shimano; Hiroto Nagaoka; Yasuji Yamada


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
204 KB
Volume
37
Category
Article
ISSN
0040-4039

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📜 SIMILAR VOLUMES


A stereoselective total synthesis of pod
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One of the foremest problems encountered in synthesis of diterpenoid resin acids is that of stereoselective introduction of methyl and carboxyl substituents at the quaternary k-position in the correct configuration relative to the C-10 angular methyl. Most previous syntheses

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✍ E.J. Corey; Hideo Kigoshi 📂 Article 📅 1991 🏛 Elsevier Science 🌐 French ⚖ 189 KB

An effective route for the total synthesis of antheridic acid (1) has been devised in which the initial chiral intermediate 7 is generated by enantioselective catalytic reduction and transformed in a stereocontrolled fashion into key intermediates 9, 10, 13, and 2.