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Stereoselective synthesis of (−)-α-multistriatin from D -glucose

✍ Scribed by Sum, Phaik-Eng; Weiler, Larry


Book ID
121311477
Publisher
NRC Research Press
Year
1982
Tongue
French
Weight
378 KB
Volume
60
Category
Article
ISSN
0008-4042

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Stereoselective total synthesis of (+)-l
✍ Noritaka Chida; Jun Takeoka; Kohji Ando; Noriko Tsutsumi; Seiichiro Ogawa 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 776 KB

The chiral and stereoselective synthesis of (+)-lactacystin 1, the first non-protein neurotrophic factor having an ct,~t-disubstituted a-amino acid structure, is described. The highly functionalized y-lactam portion possessing a tetra-substituted carbon with nitrogen in I was effectively constructed