Stereoselective synthesis of (−)-canadensolide from D-glucose
✍ Scribed by GVM Sharma; Vepachedu Sreenivasa Rao
- Book ID
- 108372462
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 393 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
The chiral and stereoselective synthesis of (+)-lactacystin 1, the first non-protein neurotrophic factor having an ct,~t-disubstituted a-amino acid structure, is described. The highly functionalized y-lactam portion possessing a tetra-substituted carbon with nitrogen in I was effectively constructed
## Abstract For Abstract see ChemInform Abstract in Full Text.
Pergamon 0957-4166(95 )00038 -0
A rather facile stereoselective total synthesis of (9S)-9-dihydroerythronolide A starting from D-glucose was achieved via coupling of Cl-C6 and C7-Cl5 segments and subsequent macrolactonizotion. The well known macrolide antibiotic erythromycin A (1) has been an attractive synthetic target for moder