Stereoselective Synthesis of α- and β-Glycosylamide Derivatives from Glycopyranosyl Azides via Isoxazoline Intermediates
✍ Scribed by Damkaci, Fehmi; DeShong, Philip
- Book ID
- 126254178
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 67 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0002-7863
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The use of phosphorothioates as DNA analogues useful in antisense-based therapy is well established and led to the development of Vitravene as the first antisense drug. Several other phosphorothioate oligonucleotides (PS-Oligos) are in clinical trials. Although Stec et al. described an elegant oxa
The use of phosphorothioates as DNA analogues useful in antisense-based therapy is well established [1] and led to the development of Vitravene as the first antisense drug. [2] Several other phosphorothioate oligonucleotides (PS-Oligos) are in clinical trials. Although Stec et al. described an elega