The stereoselective synthetic methods for anti-and syn-fused tricyclic guanidine compounds 4a and 4b were developed based on a successive 1,3-dipolar cycloaddition. Through these synthetic studies, the stereochemistry of the left-hand tricyclic guanidine unit of batzelladine F (3) was confirmed as a
β¦ LIBER β¦
Stereoselective synthesis of tricyclic guanidine, the key component of the batzelladine alkaloids
β Scribed by Kazuo Nagasawa; Takanori Ishiwata; Yuichi Hashimoto; Tadashi Nakata
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 70 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Stereoselective and efficient synthesis of tricyclic guanidine, the key component of batzelladines A and D, was accomplished based on successive 1,3-dipolar cycloadditions and successive cyclizations for the construction of the tricyclic guanidine ring.
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