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Stereoselective synthesis of tricyclic guanidine, the key component of the batzelladine alkaloids

✍ Scribed by Kazuo Nagasawa; Takanori Ishiwata; Yuichi Hashimoto; Tadashi Nakata


Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
70 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis


Stereoselective and efficient synthesis of tricyclic guanidine, the key component of batzelladines A and D, was accomplished based on successive 1,3-dipolar cycloadditions and successive cyclizations for the construction of the tricyclic guanidine ring.


πŸ“œ SIMILAR VOLUMES


Stereoselective synthesis of tricyclic g
✍ Kazuo Nagasawa; Hiroyuki Koshino; Tadashi Nakata πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 65 KB

The stereoselective synthetic methods for anti-and syn-fused tricyclic guanidine compounds 4a and 4b were developed based on a successive 1,3-dipolar cycloaddition. Through these synthetic studies, the stereochemistry of the left-hand tricyclic guanidine unit of batzelladine F (3) was confirmed as a