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Stereoselective Synthesis of the C(19)-to-C(27) Segment of Rifamycin S

✍ Scribed by Marco Born; Christoph Tamm


Publisher
John Wiley and Sons
Year
1990
Tongue
German
Weight
662 KB
Volume
73
Category
Article
ISSN
0018-019X

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✦ Synopsis


We thank PD Dr. M. Zehnder and Dr. D. Bur. lnstitut fur Anorganische Chemie der Universitiit Basel, for this measurement.


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## Abstract Chain extension of an aldehyde by two β€œpropionate” units has been attained by stereoselective allylboration with the chiral 1‐methylbutenyl boronate 3 to give, e.g., the homoallylic alcohol 6, followed by a regioselective hydroboration/carbonylation procedure to give, e.g., the epimeric