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Stereoselective Synthesis of (.+-.)-Rocaglaol Analogues.

โœ Scribed by Kai Thede; Nicole Diedrichs; Jacques P. Ragot


Publisher
John Wiley and Sons
Year
2005
Weight
14 KB
Volume
36
Category
Article
ISSN
0931-7597

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Stereoselective synthesis of thienyl and
โœ Franz Effenberger; Joachim Eichhorn ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 503 KB

The stereoselective syntheses of thienyl and furyl analogues of ephedrine starting from (R)-and (S)-cyanohydrins, respectively, are described. Addition of methyl Grignard to the O-trimethylsilyl protected optically active cyanohydrins (R)-and (S)-3 and hydrogenation of the resulting imino intermedia