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Stereoselective Synthesis of meso -2,6-Diaminopimelic Acid and Its Selectively Protected Derivatives

โœ Scribed by Gao, Yong; Lane-Bell, Patricia; Vederas, John C.


Book ID
120335188
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
254 KB
Volume
63
Category
Article
ISSN
0022-3263

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A concise, stereoselective synthesis of
โœ Philip N Collier; Ian Patel; Richard J.K Taylor ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 63 KB

The preparation of meso-2,6-diaminopimelic acid 1 is described. The key step in the synthesis is Suzuki coupling of the novel organoboron homoalanine equivalent 3 with methyl (2Z)-3-bromo-2-[(tert-butoxycarbonyl)amino]-2-propenoate 5.