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A concise, stereoselective synthesis of meso-2,6-diaminopimelic acid (DAP)

✍ Scribed by Philip N Collier; Ian Patel; Richard J.K Taylor


Book ID
104231209
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
63 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis


The preparation of meso-2,6-diaminopimelic acid 1 is described. The key step in the synthesis is Suzuki coupling of the novel organoboron homoalanine equivalent 3 with methyl (2Z)-3-bromo-2-[(tert-butoxycarbonyl)amino]-2-propenoate 5.


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✍ Yukako Saito; Takumi Shinkai; Yuichi Yoshimura; Hiroki Takahata πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons βš– 46 KB πŸ‘ 2 views

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