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Stereoselective synthesis of hydroxy-substituted tetrahydrofurans

✍ Scribed by Young Gyu Kim; Jin K. Cha

Publisher: Elsevier Science
Year: 1988
Tongue: French
Weight: 201 KB
Volume: 29
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)87821-1

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✦ Synopsis

Iodocyclizations of 4-alkene-1,3-diol derivatives proceed with high stereocontrol to provide cis 2-iodomethyl-3-hydroxy(akoxy)tetrahydrofirans.

The effect of alkoqy substituents on the diastereoselectivity has also been assessed.

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