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Stereoselective Synthesis of Fluorinated 2,3-Dihydroquinolin-4(1H)-ones via a One-Pot Multistep Transformation

✍ Scribed by Li, Feng; Nie, Jing; Wu, Jun-Wei; Zheng, Yan; Ma, Jun-An

Book ID
115468528
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
864 KB
Volume
77
Category
Article
ISSN
0022-3263

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An efficient one-pot, solvent-free method is reported for the synthesis of 2-phenyl-2,3-dihydroquinazoline-4(1H)-one as well as its o-Cl, o-OMe, m-Br, m-NO 2 , p-OH, p-NO 2 , p-CN, p-PhCH 2 O, p-Cl, p-F, p-Br, p-Me, and o,m-dichloro derivatives, using our ''as-prepared'' arc discharge fabricated Al/