Stereoselective Synthesis of Fluorescent α-Amino Acids Containing Oxine (8-Hydroxyquinoline) and Their Peptide Incorporation in Chemosensors for Divalent Zinc
✍ Scribed by Walkup, Grant K.; Imperiali, Barbara
- Book ID
- 121220038
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 79 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0022-3263
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## Abstract Artificial amino acids carrying either the chromophore of the Green Fluorescent Protein (GFP) or a modification as their side chains have been synthesized: Boc‐protected alaninyl derivatives and Fmoc‐protected __N__‐(2‐aminoethyl)glycine‐functionalized amino acids were obtained and coul
## Abstract **The cover picture shows** a chromophore of the Green Fluorescent Protein, which undergoes fast internal conversion by rotation causing the quenching of its fluorescence in solution. In contrast, the intact protein shows a high fluorescence quantum yield and there is still a need to un