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Stereoselective synthesis of C3C9 segment of soraphen A

✍ Scribed by M.K. Gurjar; A.S. Mainkar; P Srinivas


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
101 KB
Volume
36
Category
Article
ISSN
0040-4039

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Synthesis of the C1C9 segment of epothi
✍ Eckhard Claus; Axel Pahl; Peter G. Jones; Hartmut M. Meyer; Markus Kalesse 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 174 KB

The CI-C9 segment of epothilons was generated by an aldol reaction between chiral aldehyde 3 and ethyl ketone 4. Removal of the TBS protecting groups and debenzylation generated spiro ketal 13 which was analyzed by X-ray crystallography.