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Stereoselective Synthesis of C-Glycoside with a Glycosyl Dianion

✍ Scribed by Dipl.-Chem. Valentin Wittmann; Prof. Dr. Horst Kessler


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
370 KB
Volume
32
Category
Article
ISSN
0044-8249

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Chemical Synthesis of Lymphotactin: A Gl
✍ Lisa A. Marcaurelle; Laura S. Mizoue; Jill Wilken; Lisa Oldham; Stephen B. H. Ke πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 297 KB

The synthesis of a 93-residue chemokine, lymphotactin, containing eight sites of O-linked glycosylation, was achieved using the technique of native chemical ligation. A single GalNAc residue was incorporated at each glycosylation site using standard Fmoc-chemistry to achieve the first total synthesi