✦ LIBER ✦

Stereoselective synthesis of aziridine-2,3-dicarbocylic acid containing peptides as inhibitors of cysteine proteases

✍ Scribed by Tanja Schimeister

Book ID: 117628720
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 124 KB
Volume: 4
Category: Article
ISSN: 0928-0987
DOI: 10.1016/s0928-0987(97)86315-4

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inhibition of cysteine proteases by pept

Inhibition of cysteine proteases by peptides containing aziridine-2,3-dicarboxylic acid building blocks

✍ Tanja Schirmeister 📂 Article 📅 1999 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 215 KB

Mammalian cysteine proteases of the papain superfamily are interesting targets for the development of new drugs against diseases connected to abnormal degradation of muscle or bone proteins. The high nucleophilicity of the active site of these proteases as well as the characteristics of the well-kno

Aziridine-2,3-dicarboxylate Inhibitors T

Aziridine-2,3-dicarboxylate Inhibitors Targeting the Major Cysteine Protease of Trypanosoma brucei as Lead Trypanocidal Agents.

✍ Tanja Schirmeister; et al. et al. 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 12 KB 👁 1 views

Aziridine-2,3-dicarboxylate inhibitors t

Aziridine-2,3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents

✍ Radim Vicik; Verena Hoerr; Melanie Glaser; Martina Schultheis; Elizabeth Hansell 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 145 KB

1,2,3-Triazole as a Peptide Surrogate in

1,2,3-Triazole as a Peptide Surrogate in the Rapid Synthesis of HIV-1 Protease Inhibitors

✍ Ashraf Brik; Jerry Alexandratos; Ying-Chuan Lin; John H. Elder; Arthur J. Olson; 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 208 KB 👁 2 views

ChemInform Abstract: A Simple Synthesis

ChemInform Abstract: A Simple Synthesis of 4-Substituted 2-(3-Hydroxy-2-oxo-1-phenethylpropylcarbamoyl)pyrrolidine-1-carboxylic Acid Benzyl Esters as Novel Cysteine Protease Inhibitors.

✍ Seikwan Oh; Jae-Chul Jung 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

Design and synthesis of 6-substituted am

Design and synthesis of 6-substituted amino-4-oxa-1-azabicyclo[3,2,0]heptan-7-one derivatives as cysteine proteases inhibitors

✍ Nian E Zhou; Deqi Guo; Jadwiga Kaleta; Enrico Purisima; Robert Menard; Ronald G 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 105 KB