Stereoselective Synthesis of a Thymine Derivative of (S)-2-Hydroxy-4-(2-aminophenyl)butanoic Acid. A Novel Building Block for the Synthesis of Aromatic Peptidic Nucleic Acid Oligomers. -The synthesis of the title thymidine (VIII) is achieved via stereoselective reduction of the keto acid (I) using
Stereoselective Synthesis of a Thymine Derivative of ( S )-2-Hydroxy-4-(2-aminophenyl)butanoic Acid. A Novel Building Block for the Synthesis of Aromatic Peptidic Nucleic Acid Oligomers 1
β Scribed by Tsantrizos, Youla S.; Lunetta, Jacqueline F.; Boyd, Michael; Fader, Lee D.; Wilson, Marie-Claire
- Book ID
- 126307114
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 268 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
37 8C) and the mixture was filtered in a UltraFree MC 30 000 MWCO centrifugal filtration unit (Millipore) at 3500 g for 7 min at 37 8C. The concentration of free substrate in the filtrate was quantified by ICP-MS and the bound fraction was calculated as % bound ([total]-[free])/[total]. The proton T
A comparative study has been undertaken between Hmb-protected amino acid and pseudoproline building block analogues for use in the solid phase synthesis of 'difficult' peptides. Both of these derivatives act by blocking inter-and intramolecular hydrogen bonding, which has been shown to be a major ca
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v