In continuation of our program aimed at the discovery and development of natural products-based insecticidal agents, 16 novel 4alpha-alkyloxy-2-chloropodophyllotoxin derivatives were semisynthesized from podophyllotoxin, and preliminarily evaluated for their insecticidal activity against the pre-thi
✦ LIBER ✦
Stereoselective Synthesis of 4α-Alkyloxy-2-α/β-Bromopodophyllotoxin Derivatives as Insecticidal Agents
✍ Scribed by Prof. Dr. Hui Xu; Qingtian Wang; Dr. Yong Guo
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 501 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0947-6539
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## Abstract The intramolecular version of nucleophilic additon of phosphites to imines was carried out for the first time taking as an example β‐aldiminoalkylphosphites, formed from chlorophosphites and β‐aldiminoalcohols [N‐(benzylidene)‐2‐aminoethanol and R‐(+)‐N‐(benzylidene)‐2‐aminobutanol‐1].