Stereoselective Synthesis of 2-Deoxy-β-glycosides Using Anomeric O-Alkylation/Arylation
✍ Scribed by Morris, William J.; Shair, Matthew D.
- Book ID
- 126305293
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 330 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1523-7060
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📜 SIMILAR VOLUMES
a-Hydroxynaphthylthiophthalimide (1) is a suitable precursor of the reactive ortho-thioquinone 2, which can be generated in situ and trapped by glycals. The reaction is an inverse electron-demand [42] cycloaddition that occurs in a totally regioselective and highly stereoselective way. A series of d
General glycosidation methodology has been developed which can selectively provide 2acetamido-2-deoxy-a-or /3-glycosides of fl-hydroxy-a-amino acid derivatives [glucopyranoside-(8, 43), galactopyranoside-(9, 13), mannopyranoside-( 10), lactoside analogs (11, 38) and 3-O-/3-galactopyranosyl-mannopyra