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ChemInform Abstract: Stereoselective Synthesis of 2-Deoxy-β-glycosides Using Anomeric O-Alkylation/Arylation.

✍ Scribed by William J. Morris; Matthew D. Shair


Publisher
John Wiley and Sons
Year
2009
Weight
43 KB
Volume
40
Category
Article
ISSN
0931-7597

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a-Hydroxynaphthylthiophthalimide (1) is a suitable precursor of the reactive ortho-thioquinone 2, which can be generated in situ and trapped by glycals. The reaction is an inverse electron-demand [42] cycloaddition that occurs in a totally regioselective and highly stereoselective way. A series of d