Stereoselective synthesis of 1,2-diamino-1,2-diarylethane derivatives
β Scribed by I. V. Bessonov; N. A. Lozinskaya; V. R. Katashova; M. V. Proskurnina; N. S. Zefirov
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 325 KB
- Volume
- 54
- Category
- Article
- ISSN
- 1573-9171
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π SIMILAR VOLUMES
## Abstract The reaction substrate (I) with various arenes is mediated by BF~3~Β·Et~2~O or TFA with comparable yields.
Conformationally constrained bis(glycines) as trans derivatives of cyclopropane have been prepared in stereoselective syntheses. (S)-4-Benzyl-2-oxazolidinone was used as a chiral auxiliary, trisyl azide was the electrophilic source of amine nitrogen. Four stereogenic centers were created. A related
Low temperature nitrations of 2-methylimidazole gave in addition to the known 2-methyl-5(4)-nitroimidazole (1), 2-(dinitromethylene)-5,5-dinitro-4-imidazolidinone (3) and parabanic acid (2). The tetranitro compound 3 was also obtained by nitration of 2-methyl-4,5-dihydro-(lH)-5-imidazolone (8). Ther