Stereoselective synthesis of 10,11-dihydro-leukotriene B4 and related metabolites
β Scribed by Yuichi Kobayashi; Yuji Nakayama; G. Biju Kumar
- Book ID
- 108386970
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 235 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
The stereoselectivity of the reduction of 5-carbamoyl-l0, I 1-dihydro-1 l-oxo-SH-dibenz[bflazepine-lO-yl acetate (6), prepared in two steps from 10, I l-dihydro-lO-oxo-5H-dibenz[hflazepine-5-carboxamide (4), has been studied. Among the reagents used, diisobutylaluminum hydride (DIBAH) was found to g
The mass spectrometry quantification and metabolic studies of leukotriene B 4 (LTB 4 ) in biological fluids require standards labelled with stable isotopes. This paper describes the synthesis of LTB 4 labelled with 13 C in positions 6, 7, 10 and 11 ( % 1). These labelled carbons come from 13 C 2 -ac