Stereoselective Synthesis of 1-Bromo-1-fluorostyrenes
β Scribed by Aleksey V. Shastin; Vasiliy M. Muzalevsky; Elizabeth S. Balenkova; Valentine G. Nenajdenko
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 20 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Bromo-1-alkenes were stereoselectively prepared in high yields in a short reaction time (0.2-1.0 min) by microwave irradiation of the corresponding 2,3-dibromoalkanoic acids in DMF in the presence of triethylamine.
We describe a synthesis of 2E-pyrrole l-oxides (3) from the 3-bromopyrroline l-oxides (2). Bromination in the 3-position of 1-pyrroline l-oxides appears to be a general reaction and the 2-cyano-1-pyrroline l-oxides (1) undergo reaction with E-bromosuccinimide (NBS) to form the monobromo nitrones (2)