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Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain

โœ Scribed by Bapurao B. Shingate; Braja G. Hazra; Deepak B. Salunke; Vandana S. Pore; Fazal Shirazi; Mukund V. Deshpande


Book ID
113582972
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
351 KB
Volume
46
Category
Article
ISSN
0223-5234

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๐Ÿ“œ SIMILAR VOLUMES


Regio and stereochemically controlled ri
โœ J.R. Schauder; A. Krief ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 255 KB

This epoxide was obtained stereoselectively (> 95% ) on reaction of corresponding C-2O,C-22 olefin with osmium tetroxide (1.2 eq., 10ยฐ,1hr,85X yield) followed by basic cyclisation of the resulting C-2O,C-22 diol via its C-22 monomesylate (74% overall yield).