Stereoselective syntheses of cytoxazone, a novel cytokine modulator, and its stereoisomers
β Scribed by Yasuharu Sakamoto; Akiko Shiraishi; Jeong Seonhee; Tadashi Nakata
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 254 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
Cytoxazone, a novel eytokine modulator, and its stereoisomers were stereoselectively synthesized via stereocontrolled introduction of an azide group and direct construction of the 2-oxazolidinone ring from an azide carbonate by reductive cyclization.
π SIMILAR VOLUMES
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Cytoxazone [(4R,5R)-(-)-5-hydroxymethyl-4-(4-methoxyphen-employing the Sharpless asymmetric dihydroxylation as the key reaction in 26% overall yield (7 steps). yl)-2-oxazolidinone, 1], a new immunosuppressant, was synthesized by starting from p-methoxycinnamyl alcohol (2) In 1998 Osada and co-worke
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v