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Stereoselective Sonogashira Coupling of 1,1-Dibromo-1-alkene.

โœ Scribed by Jun'ichi Uenishi; Katsuaki Matsui; Hirohisa Ohmiya


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
33
Category
Article
ISSN
0931-7597

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Stereoselective Hydrogenolysis of 1,1-Dibromo-1-alkenes and Stereospecific Synthesis of Conjugated (Z)-Alkenyl Compounds. -The Pd-catalyzed hydrogenolysis of 1,1-dibromo-1-alkenes with Bu 3 SnH proceeds stereoselectively yielding (Z)-1-bromo-1-alkenes. Alkenyl-and alkynylconjugated 1,1-dibromo-1-al