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Stereoselective Reductive Rearrangement of α-Hydroxy Epoxides: A New Method for Synthesis of 1,3-Diols 1

✍ Scribed by Tu, Yong Qiang; Sun, Liang Dong; Wang, Ping Zhen


Book ID
127077515
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
200 KB
Volume
64
Category
Article
ISSN
0022-3263

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The diastereoselective reduction of acyclic B-alkoxy ketones with lithium aluminum hydride in the presence of lithium iodide has been studied and found to provide syn-1,3-diol derivatives with high diastereoselection. -The stereocontrolled formation of 1,3-diols is of great interest to synthetic che