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Reduction of .beta.-hydroxy ketones with catecholborane. A stereoselective approach to the synthesis of syn-1,3-diols

โœ Scribed by Evans, David A.; Hoveyda, Amir H.


Book ID
120930280
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
404 KB
Volume
55
Category
Article
ISSN
0022-3263

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Stereoselective reduction of ฮฒ-alkoxy ke
โœ Yuji Mori; Miki Kuhara; Akio Takeuchi; Makoto Suzuki ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 238 KB

The diastereoselective reduction of acyclic B-alkoxy ketones with lithium aluminum hydride in the presence of lithium iodide has been studied and found to provide syn-1,3-diol derivatives with high diastereoselection. -The stereocontrolled formation of 1,3-diols is of great interest to synthetic che