Reduction of 7-chlorobicyclo[3.2.0]hept-
Reduction of 7-chlorobicyclo[3.2.0]hept-2-en-6-ones catalysed by 3α, 20β-hydroxysteroiddehydrogenase
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H. Geoff Davies; Thomas C.C. Gartenmann; Jeff Leaver; Stanley M. Roberts; Michae
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Article
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1986
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Elsevier Science
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French
⚖ 110 KB
The enzymes are stirred together with Eupergit-C (Dumas Chemicals) in 1M phosphate buffer (pH 7.5) over 96 h at 4OC. 10. 7endo-Chloro-7exo-methylbicyclo[3.2.0]hept-2~en-6-one was reduced by HSDH to give optically pure-&do-alcohol.