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Stereoselective reactions of N-acyl-N,O-acetals with 2-(trimethysilyloxy)furan

✍ Scribed by Kenn E. Harding; M. Todd Coleman; Lee T. Liu

Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
262 KB
Volume
32
Category
Article
ISSN
0040-4039

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✦ Synopsis

Reaction of ocyclrc chtral N-acyl-N,O-metals with 2-(aanethylsr~ylo~)~~~n and EF, Et20 produces 4-(nartnoalkyl)-2-bnten-4-ali~,~ in 3070 to 6270 y&d and vnrinbla dmrtermmeric excesses of the syn (tftrro) stereoisomer. Selectivity is dependent on the structure ofN-ncyl-N,O-metal used.

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